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How To Sleep While Taking Phentermine: A Guide

Phentermine, also known as Adipex P or Lomaira, is an increasingly common weight loss medication used by men and women throughout the country. If you are about to start a course of it, though, several questions must be answered. Knowing how to sleep while taking Phentermine should be at the top of your agenda.

Alternatively, if your sleep patterns have suffered since taking Phentermine, this guide on how to sleep while taking Phentermine should help you get things back on track.

how to improve sleep

How To Improve Sleep While Taking Phentermine

Phentermine is a prescription-only medication and, in most cases, you cannot lose your job for taking it legally. However, this may change if you become unable to complete your daily responsibilities as required. It is one of many reasons why you will want to prevent the medication from impacting your sleep patterns. 

Prescription phentermine is generally safe and well-tolerated with no lasting side effects. Still, it is very common for patients to experience poor sleep patterns during the course of their weight loss medication. This can subsequently impact appearances, health, and happiness. 

As a note, decreased quality of sleep is actually linked with weight gain. This means that if you are taking phentermine to lose weight, but lose sleep instead, you could be diminishing the effectiveness of the drug.

Here is a list of six simple steps of how to sleep while taking Phentermine;

improve sleep surroundings

Improve Your Sleep Surroundings

Getting a good night’s sleep is essential for overall health and well-being, and having a comfortable sleep setting can greatly improve the quality of your sleep. There are several key factors to consider when creating a comfortable sleep environment.

Firstly, blocking excess light is important, as exposure to light can disrupt your natural sleep-wake cycle. Using curtains or blinds to block out outside light, or wearing an eye mask, can help create a darker sleeping environment.

Secondly, having comfortable bedding, including a supportive mattress and soft, breathable sheets and pillows, can help ensure a restful night’s sleep. It’s also important to choose bedding that suits your personal preferences, such as the right level of firmness or softness.

Thirdly, using a white noise machine or other soothing sounds, such as calming music or nature sounds, can help drown out background noise and create a peaceful sleep environment.

Fourthly, keeping the temperature in your bedroom cool, between 60-67 degrees Fahrenheit, can help promote restful sleep. This temperature range has been shown to optimize sleep quality and help regulate the body’s natural sleep-wake cycle.

Lastly, breathing strips can be helpful for those who struggle with snoring or breathing difficulties during sleep. They work by gently opening up the nasal passages, allowing for easier breathing and a better night’s sleep.

sleep aids

Consider Sleep Aids

When Phentermine increases your energy levels or makes it difficult for you to switch off at night, the logical step is to counteract this with a sedative or alternative sleep aid. There are several possible options to consider, although Melatonin is the most common.

While no known interactions between Phentermine and Melatonin have been scientifically shown, research is still inconclusive. Therefore, you should always consult an expert before introducing any other medication to your weight loss strategy. Other supplements that can help with sleep include magnesium, calcium, and ashwagandha.

take early

Take Phentermine Earlier In The Day

The half-life of phentermine is an astounding 20 hours, meaning that 20 hours after consumption, half of the drug is still present in your system, with peak onset effects appearing between 2-4 hours. 

For this reason, taking the medication as early as possible in the morning is highly advised. In fact, waking up a few hours before you usually do could make all the difference between getting a restful night’s sleep and being stuck up all night.

avoid caffeine

Avoid Caffeine

When looking for answers on how to sleep while taking phentermine, avoiding caffeine is a vital factor. Phentermine will give you an energy boost, so the last thing you need is the extra energy gained from caffeine. Avoid coffee, tea, and other caffeine-high sources.

Caffeine and Phentermine is a combination that could also lead to high blood pressure, an increased heart rate, or chest pain. While avoiding the stimulant for a few hours before bed is essential, you should probably try to minimize your intake throughout the day.

If you do feel the need for a cup of joe, try not to consume any caffeine after 12:00pm. Since the half-life of caffeine is around 4-6 hours, doing so will ensure that any caffeine is flushed from your system by the time you need to go to sleep.

prepare for sleep

Let Yourself Prepare For Sleep

Finally, you should try to establish a winning sleep pattern. Going to bed at the same time can deliver a plethora of benefits. So, building an effective evening routine should be on the agenda.

Additionally, blue light (the type projected from electronic screens) has been shown to interfere with the brain’s ability to secrete melatonin, a neurotransmitter responsible for helping you fall asleep. For this reason, minimizing blue light consumption a few hours before bedtime will help your brain relax and get ready for sleep. 

If you absolutely must look at screens before bedtime, it is advised to use blue light glasses, or switch your device to a nighttime mode.

Some other steps you can take may include having an evening bath or enjoying light yoga and meditation. Writing down your plan for the following day before moving to the bedroom may also help. Some trial and error may be needed, but the potential rewards are incredible.


Is Insomnia Common When Taking Phentermine?

Side effects can be alarming when taking any type of prescription medication. However, insomnia and damaged sleep patterns are the second most-common side effect of taking Phentermine. This is largely attributed to the fact that it is a central nervous system (CNS) stimulant that increases your energy levels as a byproduct of its primary function of suppressing appetites. 

Most patients that experience insomnia after starting Phentermine can expect the symptoms to last for the first few days while some may see this extend to a few weeks. If you still suffer from insomnia after two months of starting the course, you may wish to consult your doctor.


Can You Take Melatonin While on Phentermine?

There are no known drug interactions between melatonin and phentermine, making it safe to supplement with melatonin while taking phentermine. In fact, supplementing with melatonin can be a great addition to your sleep routine, as it can help regulate your sleep-wake cycle and improve the quality of your sleep.

Melatonin is a hormone that is naturally produced by the body to regulate sleep and wakefulness. However, many people may have difficulty producing enough melatonin, especially if they have trouble falling asleep or staying asleep.

Supplementing with melatonin can help regulate your sleep-wake cycle and improve the quality of your sleep. It can also help you fall asleep faster and stay asleep longer, which can be especially helpful if you are taking phentermine, as sleep disturbances are a common side effect of the medication.

It is important to note that while melatonin is generally safe and effective for most people, it is not recommended for everyone. It may interact with certain medications or medical conditions, so it is important to talk to your healthcare provider before starting to take melatonin or any other supplements.

Can You Take ZzzQuil While on Phentermine?

There are no known drug interactions between Zzzquil and phentermine, so it is generally safe to use these medications together. However, it is important to note that frequent or long-term use of Zzzquil is not recommended, as it can lead to dependence on the medication to fall asleep.

Zzzquil is an over-the-counter sleep aid that contains the active ingredient diphenhydramine, which can cause drowsiness and help you fall asleep. While it can be effective in the short term, using it on a regular basis can lead to a decrease in its effectiveness and may even cause dependence.

Instead of relying on medication to help you fall asleep, it is recommended to establish healthy sleep habits, such as maintaining a regular sleep schedule, avoiding caffeine and alcohol before bedtime, and creating a comfortable sleep environment. If you continue to have trouble sleeping despite these measures, it may be helpful to speak with a healthcare professional who can provide additional guidance and support.


Phentermine is a commonly prescribed medication for weight loss, as it can help suppress appetite and boost metabolism. However, one common side effect of phentermine is difficulty sleeping, which can be attributed to its long half-life of 20 hours.

To help combat this side effect, it is recommended that patients take phentermine as early as possible in the day, such as in the morning, to allow the effects of the medication to wear off before bedtime. Additionally, practicing healthy sleep habits, such as establishing a regular sleep schedule, avoiding caffeine and alcohol before bedtime, and creating a comfortable sleep environment, can also help promote restful sleep.

It is important to note that while phentermine can be an effective weight loss drug, it should only be used as part of a comprehensive weight loss plan that includes healthy eating habits and regular exercise. It is also important to use phentermine under the guidance of a healthcare professional and to follow the recommended dosage and usage instructions to minimize the risk of side effects.

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